Changzhou National High-tech Zone is located in the north of Changzhou City. It is one of the first national high-tech zones approved by The State Council in November 1992. In April 2002, Changzhou New North District was established on the basis of the high-tech zone, and the management system of "two brands and one team" was implemented. At present, it has jurisdiction over 5 towns and 5 streets, a provincial economic development zone and a comprehensive bonded zone, with an area of 508.91 square kilometers and a permanent population of 90.03 million.

In 2022, under the strong leadership of Changzhou Municipal Party Committee and Municipal Government, the High-tech Zone will adhere to the general tone of seeking progress while maintaining stability, comprehensively coordinate epidemic prevention and control and economic and social development, coordinate development and security, maintain a stable and orderly social situation, and steadily advance high-quality development, achieving a gross regional product of 199.06 billion yuan, an increase of 4% (calculated at comparable prices); Per capita GDP exceeded 220,000 yuan; Revenue in the general public budget was 13.25 billion yuan, an increase of 5%. The total output value of industries above designated size reached 342.97 billion yuan, an increase of 11.9% year-on-year, ranking first in the city.